• Biotech Beat: Celldex Therapeutics (CLDX)

    Biotech Beat: Celldex Therapeutics (CLDX)

    Biotech stocks have had a rough break since the Turing fiasco in late 2015. While this negative publicity reflects a moderate amount of risk to large pharmaceutical companies with broad drug portfolios, it has created myriad investment opportunities in early stage companies. Here we discuss Celldex Therapeutics (NASDAQ:CLDX), a stock whose current drug pipeline shows tremendous and imminent […]

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  • Why do babies put everything in their mouths?

    Why do babies put everything in their mouths?

    Spend enough time around babies and you’ll notice they’ll put just about anything into their mouth. Many people pass this off as an infant’s way of feeling their surroundings. Yet, this argument does not capture the science behind the world’s cutest phenomenon. It’s a common scene for any new parent – Their baby, happily entertained on the floor, grabs a close-by […]

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  • Human cell in stag’s clothing – How a simple molecular ruse can train our immune system to fight cancer.

    Human cell in stag’s clothing – How a simple molecular ruse can train our immune system to fight cancer.

    One of the most tragic of the Greek myths is that which recounts the death of Actaeon –the hunter who was transformed into the hunted. This tale works as a strong metaphor to explain the mechanism behind a powerful new cancer-fighting therapy. While out on a hunt, Actaeon made the fatal mistake of stumbling upon the […]

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  • This little piggy could save your life

    This little piggy could save your life

    There is a fair share of non-trivial differences between humans and pigs, yet, things are a bit more ambiguous at the cellular level. Finding the differences at this resolution could potentially save the lives of millions of people in line for organ transplants. On average, 18 people die a day because they did not receive an organ transplant. This […]

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  • Unleashing cancer-fighting bacteria – a blistering new discovery

    Unleashing cancer-fighting bacteria – a blistering new discovery

    Superbly demonstrating out-of-the-box thinking, scientists have re-purposed tiny soil germs into cancer-fighting bacteria. While scientific evidence for a cancer therapy using Clostridium bacteria has festered for years, the first application in humans is turning heads. For decades, medical researchers have run into a wall when treating cancer. No matter how exquisite or advanced a new cancer […]

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  • Ebola, InFLUenza, and AIDs Oh My! – Viral pathogens 101

    Ebola, InFLUenza, and AIDs Oh My! – Viral pathogens 101

    The Ebola endemic is wreaking havoc on western Africa and continues to spread at an alarming rate. The devastation caused by this virus is a clear example of how dangerous these microscopic pathogens can be. Here we outline the basics of what a virus is and how researchers are inventing new ways to keep them at […]

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  • The Achilles’ Heel of Ebola discovered while medicine development lags far behind

    The Achilles’ Heel of Ebola discovered while medicine development lags far behind

    As the ebola virus rages through central Africa with an unprecedented number of infections, the rest of the developed world is left wondering what kind of danger this virus poses to us and our first-world health systems. In the midst of sometimes exaggerated fears of a pandemic, scientists are racing to create a medicine for the disease. Despite […]

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  • How $93,000 dupes the immune system into fighting prostate cancer

    How $93,000 dupes the immune system into fighting prostate cancer

    Vaccinating against cancer has always been a simple idea that appeared impossible to execute. While it is easy to vaccinate against cancer-causing viruses such as HPV or Hepatitus A/B, the development of a true cancer vaccine has only seen one victory with Sipuleucel-T (Provenge) in 2010. Since its approval as a Category 1 drug, Provenge has been […]

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  • Part 1: Harnessing the immune system to fight cancer

    Part 1: Harnessing the immune system to fight cancer

    In this series we will review developments in the emerging field of cancer immunotherapy. Considered by both doctors and scientists to be the most promising treatment for cancer, immunotherapy may be the only treatment that has the potential to cure cancer. What is immunotherapy and how does it work? In Part 1 we discuss the fundamental science […]

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  • Between hair loss and medicine for the rich, how did cancer drugs come to be?

    Between hair loss and medicine for the rich, how did cancer drugs come to be?

    While news reporting tends to lump cancer medicine as a group of hair loss-inducing and extremely costly drugs, there are profound differences between the different types. In general, there are three types of therapy, chemotherapy is the oldest and simplest, while systemic medicine and targeted biologics are relatively new to the field. The biological mechanism […]

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