• John McCain, Glioblastoma & Novocure’s Electric Cancer-killing Machine

    John McCain, Glioblastoma & Novocure’s Electric Cancer-killing Machine

    Following a blood clot removal, John McCain was diagnosed with Glioblastoma, a cancer with even worse prognosis than pancreatic cancer. For decades, patients diagnosed with Glioblastoma multiforme (GBM) received an almost certain death sentence, with average survival times measured in months. Yet the approval of the most scifi-esque cancer therapy to date, Tumor-treating fields (Optune, […]

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  • Don’t call it a comeback – rethinking, drug repurposing

    Don’t call it a comeback – rethinking, drug repurposing

    The next big cancer drug may already be stocked on our pharmacy shelves without us even know it, ready to take a punch out of some new disease! Here, we consider the robust potential of drug repurposing (AKA drug repositioning, re-profiling, re-tasking or therapeutic switching). Even prior to dawn of modern medicine, it was common practice to investigate if […]

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  • Biotech Beat: Celldex Therapeutics (CLDX)

    Biotech Beat: Celldex Therapeutics (CLDX)

    Biotech stocks have had a rough break since the Turing fiasco in late 2015. While this negative publicity reflects a moderate amount of risk to large pharmaceutical companies with broad drug portfolios, it has created myriad investment opportunities in early stage companies. Here we discuss Celldex Therapeutics (NASDAQ:CLDX), a stock whose current drug pipeline shows tremendous and imminent […]

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  • Which sex has it worse when it comes to cancer?

    Which sex has it worse when it comes to cancer?

    While the age-old battle of the sexes will never be decisively won, there are certain arenas where the balance is strongly tipped. Cancer risk is one of these. Check out the list below to see where each sex stands in the fight against “the worst scourge of mankind.” 1. Women suffer from more sex-specific cancers. The […]

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  • Want to reduce your cancer risk? Take this pill

    Want to reduce your cancer risk? Take this pill

    Recent breakthroughs in medicine have shed light on an apparent scientific paradox: While inflammation is necessary for our survival, it is also a fundamental cause of death. Long term effects of inflammation are seen throughout the body, from heart disease to diabetes to cancer. Fortunately for aspiring centenarians, a common over-the-counter anti-inflammatory medicine can reduce your risk of dying from the top three […]

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  • Part 2: Aspirin and cancer prevention

    Part 2: Aspirin and cancer prevention

    Part 1: Inflammation is a fundamental cause of death. Unaware of its beneficial effects, our ancestors only knew inflammation as the cause of pain and fever. They found a natural cure in the bark of the Willow tree. Centuries later in 1971, John Robert Vane discovered how the active ingredient from Willow bark, Salicylic acid, reduces inflammation. Salicylic […]

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  • 9 things breast cancer awareness month missed

    9 things breast cancer awareness month missed

    While breast cancer awareness month generates a lot of good press and brings in quite a few research dollars, it generally does not convey the facts people really should know about our beloved mammary glands. As everyone starts washing the pink off their clothes and start growing out their beards, here are a few of the […]

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  • Human cell in stag’s clothing – How a simple molecular ruse can train our immune system to fight cancer.

    Human cell in stag’s clothing – How a simple molecular ruse can train our immune system to fight cancer.

    One of the most tragic of the Greek myths is that which recounts the death of Actaeon –the hunter who was transformed into the hunted. This tale works as a strong metaphor to explain the mechanism behind a powerful new cancer-fighting therapy. While out on a hunt, Actaeon made the fatal mistake of stumbling upon the […]

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  • When citric acid causes cancer: Agios Pharmaceuticals and IDH inhibitors

    When citric acid causes cancer: Agios Pharmaceuticals and IDH inhibitors

    Agios Pharmaceuticals (AGIO) is at the forefront of drug development against a central path of cancer’s evolution – its metabolism. With two drugs in Phase I testing, Agios is poised to enter an uncharted field of cancer treatment. This audacious attempt at cancer treatment comes with substantial risks, but may end up up paying off. Up to this point, all […]

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  • Junk DNA builds a new LiNC to cancer

    Junk DNA builds a new LiNC to cancer

    The human genome project has led to quite a few surprises. One of the most astonishing discoveries is that only 2% of our DNA behaves in the way that scientists expect – by coding for proteins. The remainder of the genome was given the moniker “junk DNA” by Susumu Ohno. Unfortunately for Susumu’s reputation, scientists are […]

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